Dr. Hanna LU
Assistant Professor (Non-clinical)

Dr. LU Hanna
Assistant Professor (Non-clinical)

路翰娜博士
PhD (CUHK)

Fax: (852) 2667-5464
Email: hannalu@cuhk.edu.hk
ORCID: 0000-0002-9090-258X
Personal Website: http://thebrainx.com

OTHER POSITIONS:
  • Deputy Director of Neuromodulation Clinic
  • Visiting Fellow: National Laboratory of Pattern Recognition, Chinese Academy of Sciences
  • Honorary Professor: The Affiliated Brain Hospital of Guangzhou Medical University
  • Associate Researcher: Shenzhen Research Institute (SZRI) CUHK (By Courtesy)
  • Editorial Board Members:
  • Associate Editor:
RESEARCH INTERESTS:
  • Individualized non-invasive brain stimulation 
  • Computational models of brain age 
  • Precise measurement of neurocognitive functions 
  • Mechanisms of cognitive ageing and resilience 
CURRENT PROJECTS:
  1. Radiomics for the Prediction of Brain Age, Cognitive Maintenance and Healthy Longevity Funded by Research Grants Council (RGC)-US. National Academy of Medicine (NAM). Capacity: PI. Study duration: 01/10/2023-30/09/2024. 
  2. Transcranial alternating current stimulation for mild neurocognitive disorders due to Alzheimer’s disease, Funded by Research Grants Council (RGC)-General Research Fund (GRF). Capacity: PI. Study duration: 01/01/2022-31/12/2023. 
  3. Developing the geometric model of network-based cortical complexity, Funded by National Laboratory of Pattern Recognition, Chinese Academy of Sciences (CAS). Ref. number: 202100034. Capacity: PI. Study duration: 01/2021-12/2022. 
  4. A novel computational framework for optimizing disease-specific transcranial brain stimulation model (Reference No.: 4054645), Funded by CUHK Direct Grant for Research. Capacity: PI. Study duration: 24/06/2021 – 23/06/2022. 
  5. Decoding the cognitive trajectory of Hong Kong SuperAgers: a six-year follow-up study, Funded by CUHK Direct Grant for Research. Ref. number: 4054569. Capacity: PI. Study duration: 25/06/2020-24/06/2021 
  6. LANDSCAPE 2.0: A Multimodal Neuroimaging Study (Funded by CUHK Direct Grant for Research 2018/2019. Ref. number: 4054495. Capacity: PI. Study duration: 24/06/2019-24/06/2020) 
  7. Personalized prediction of transcranial magnetic stimulation clinical response in patients with treatment-refractory depression using neuroimaging biomarkers and machine learning, Funded by Research Grants Council (RGC)-General Research Fund (GRF). Capacity: Co-I. PI: Prof. Sandra Sau Man Chan, CUHK.  
  8. Transcranial Direct Current Stimulation in Post-Stroke Fatigue: A Double-blind Randomised Control Trial, Funded by Research Grants Council (RGC)-General Research Fund (GRF). Capacity: Co-I. PI: Prof. Wai Kwong Tang, CUHK. 
  9. Can increasing participation in habitual intellectual activities enhance functional connectivity of default mode network in community-living Chinese adults with subjective cognitive decline? A randomized controlled trial. (Funded by Early Career Scheme, RGC 2019/2020. Capacity: Co-I. PI: Dr. Allen Lee, CUHK. Ref. number: 24114519. Study duration: 1/1/2020-31/12/2021) 
AWARDS:
  • 2023 Healthy Longevity Catalyst Awards (Hong Kong) 
  • 2022 Travel Awards, The 63st Annual Meeting of the Japanese Society of Neurology (JSN) 
  • 2021 Best Paper Awards, China Association of Gerontology and Geriatrics (CAGG) 
  • 2021 Gold Award on the 19th Asian Oceanian Congress of Neurology (AOCN) 
  • 2021 Fellowship from Japanese Society of Radiology (JSR) 
  • 2021 Young Education Scholarship (YES) Awards on the 19th Asian Oceanian Congress of Radiology (AOCR) 
  • 2020 Travel Grants on the 61st Annual Meeting of the Japanese Society of Neurology (JSN) 
  • 2019 Best Paper Awards, China Association of Gerontology and Geriatrics (CAGG) 
  • 2019 Travel Grants on the 60th Annual Meeting of the Japanese Society of Neurology (JSN) 
  • 2019 Travel Grants on the 3rd International Taiwanese Congress of Neurology (ITCN) & Annual Meeting of Taiwan Neurological Society 
  • 2019 Training Fellowships from the National Institute for Physiological Sciences (NIPS) (Japan) 
  • 2018 Champion & Young Investigator Awards on the International Alzheimer’s Disease Conference 
  • 2018 Young Investigator Awards on The 15th Meeting of the Asian-Pacific Society for Neurochemistry 
  • 2015 Performance Award on the 22nd International Student Congress of [Bio] Medical Sciences 2015 
  • 2015 Paper Award on the 15th Congress of Chinese Cerebrovascular Diseases 
  • 2015 Paper Award on “Putting Aging Research and Clinical Practice in Cultural Context”: US-Hong Kong Conference 
SELECTED PUBLICATIONS (Neuropsychology):
  1. Lu H*, Li J, Ni X.
    Promoting Resilience in the Age of COVID-19 Pandemic: A New Era of Strategic Foresight.
    Aging and Disease 2021; 12(1): 1-2.
  2. Lu H*.
    Caution of variability: Domain-specific cognition measured by Montreal Cognitive Assessment in normal ageing and prodromal dementia.
    International Journal of Geriatric Psychiatry 2020; 35(6), 686-687.
  3. Lu H*, Lam LC.
    Associations between intra-individual variability and Montreal Cognitive Assessment (MoCA) in cognitive ageing and prodromal dementia: A domain-specific perspective.
    Parkinsonism & Related Disorders 2018; 48:102-103.
  4. Lu H*, Lam LC.
    Impacts of ‘two-level’ variability on the differential power for Montreal Cognitive Assessment (MoCA) in prodromal dementia.
    Journal of Neurology, Neurosurgery and Psychiatry 2017; 88(2): 186-187.
  5. Lu H*, Chan SS, Lam LC.
    ‘Two-level’ measurements of processing speed as cognitive markers in the differential diagnosis of DSM-5 mild neurocognitive disorders (NCD).
    Scientific Reports 2017; 7.
  6. Lu H*.
    Intra-and inter-individual variability of information processing speed in adults with neurocognitive disorders.
    F1000 Research 2017; 6.
  7. Lu H*, Chan SS, Fung AW, Lam LC.
    Utility of Montreal Cognitive Assessment (Hong Kong Version) in the diagnosis of mild neurocognitive disorders (NCD): NCD due to Alzheimer Disease (NCD-AD) and NCD due to Vascular Disease (NCD-Vascular).
    Journal of the American Medical Directors Association 2016; 17(4): 366
  8. Lu H, Fung AW, Chan SS, Lam LC.
    Disturbance of attention network functions in Chinese healthy older adults: an intra-individual perspective.
    International Psychogeriatrics 2016; 28(2): 291-301.
  9. Lu H*, Chan SS, Fung AW, Lam LC. Efficiency of attentional components in elderly with mild neurocognitive disorders shown by the attention network test.
    Dementia and Geriatric Cognitive Disorders 2016; 41(1-2): 93-98.
  10. Lu H*, Law WY, Fung AW, Lam LC.
    Evaluating the Montreal Cognitive Assessment (MoCA) and its subtests for DSM-5 mild neurocognitive disorders (NCD): Does age have an effect on the screening accuracy?
    Journal of Psychosomatic Research 2016; 85: 26-27.
  11. Lu H*, Chan SS, Lam LC.
    Associations between intra-Individual variability of reaction time and cognitive function in cognitively normal senior adults: still beyond good or bad?
    Geriatrics 2016; 1(2): 13.
SELECTED PUBLICATIONS (Neuroimaging):
  1. Li, J.,  Lu, H*.
    MRI‐informed cortical features for brain age prediction in age‐specific adulthoods.
    Human Brain Mapping 2022. (In Press)
  2. Lu H*.
    Quantifying Age-Associated Cortical Complexity of Left Dorsolateral Prefrontal Cortex with Multiscale Measurements.
    Journal of Alzheimer’s Disease 2020; 76(2): 505-516.
  3. Lu H*, Ma SL, Wong SW, Tam CW, Cheng ST, Chan SS, Lam LC.
    Aberrant interhemispheric functional connectivity within default mode network and its relationships with neurocognitive features in cognitively normal APOE ε 4 elderly carriers.
    International Psychogeriatrics 2017; 29(5): 805-814.
  4. Lu H*.
    Mapping the brain: the leading projects of brain science in the era of big data (in Chinese).
    Chinese Journal of Psychiatry 2017; 50(2):157-160.
  5. Lu H*, Ma SL, Chan SS, Lam LC.
    The effects of apolipoprotein ε 4 on aging brain in cognitively normal Chinese elderly: a surface-based morphometry study.
    International Psychogeriatrics 2016; 28(9): 1503-1511.
  6. Lu H*, Ning YP.
    When neuroscience meets network thinking: new perspective on brain disorders (in Chinese).
    Chinese Journal of Neuromedicine 2014; 13(12): 1292-1296.
  7. Lu H*, Ning YP.
    Advances in brain activity mapping (BAM) and brain connectome (in Chinese).
    Chinese Journal of Psychiatry 2014; 47(3): 179-182.
SELECTED PUBLICATIONS (Neuromodulation)
  1. Lu H*, Li J, Yang NS, Lam LCW, Ma SL, Wing YK, Zhang, L.
    Using gamma-band transcranial alternating current stimulation (tACS) to improve sleep quality and cognition in patients with mild neurocognitive disorders due to Alzheimer’s disease: A study protocol for a randomized controlled trial.
    PLoS ONE 2023, 18(8), e0289591.
  2. Lu H, Chan SS, Chan WC, Lin CC, Cheng PW, Lam LC.
    Randomised Controlled Trial of TDCS on Cognition in 201 Seniors with Mild Neurocognitive Disorder.
    Annals of Clinical and Translational Neurology 2019; 6(10): 1938-1948.
  3. Lu H*, Lam LC, Ning YP.
    Toward Personalized Brain Stimulation: Advances and Challenges.
    CNS Neuroscience & Therapeutics 2019; 25(11): 1219-1221.
  4. Lu H*, Lam LCW.
    Cathodal skin lesions induced by transcranial direct current stimulation (tDCS).
    Neuromodulation: Technology at the Neural Interface 2019; 22(8), 989-991.
  5. Lu H*, Chan SS, Lam LC, Cheng CP, Chan WC, He HB, Zhao SH, Ning YP.
    Towards individualized psychiatric practice: the legacy of neurotherapeutics (in Chinese).
    Chinese Science Bulletin 2018; 63: 2592-2598.
SELECTED PUBLICATIONS (Neuropsychology & Neuroimaging):
SELECTED PUBLICATIONS (Neuroimaging & Neuromodulation):
  1. Lu H*, Li J, Zhang L, Meng L, Ning Y, Jiang T.
    Pinpointing the precise stimulation targets for brain rehabilitation in early-stage Parkinson’s disease.
    BMC Neuroscience 2023, 24(1), 1-12.
  2. Lu H*, Li J, Chan SSM, Yue WWY, Lam LCW.
    Decoding the radiomic features of dorsolateral prefrontal cortex in individuals with accelerated cortical changes: implications for personalized transcranial magnetic stimulation.
    Journal of Medical Imaging 2023, 10(1), 015001-015001.
  3. Lu, H*., Chan, S. S. M., Ma, S., Lin, C., Mok, V. C. T., Shi, L., & Lam, L. C. W.
    Clinical and radiomic features for predicting the treatment response of repetitive transcranial magnetic stimulation in major neurocognitive disorder: Results from a randomized controlled trial.
    Human Brain Mapping 2022, 43(18), 5579-5592.
  4. Lu, H*.
    Radiomics-informed modeling for transcranial ultrasound stimulation: Age matters.
    Frontiers in Neuroscience 2022, 924.
  5. Lu, H*.
    MRI-Based Geometric Modeling for Personalized Transcranial Magnetic Stimulation in Age-Related Neurodegenerative Diseases.
    Frontiers in Neuroscience 2021, 860.
  6. Lu H*, Li J, Zhang L, Chan SSM, Lam LCW.
    Dynamic changes of region-specific cortical features and scalp-to-cortex distance: implications for transcranial current stimulation modeling.
    Journal of NeuroEngineering and Rehabilitation 2021, 18(1): 1-12.
  7. Lu H*.
    Developing and aging: A tale of two stages.
    CNS Neuroscience & Therapeutics 2020; 26(2), 281.
  8. Lu H*, Chan SS, Lam LC.
    Localized Analysis of Normalized Distance from Scalp to Cortex And Personalized Evaluation (LANDSCAPE): Focusing on Age-and Dementia-specific Changes.
    Journal of Alzheimer’s Disease 2019, 64(7): 1331-1341.
  9. Lu H*, Lam LC, Ning YP.
    Scalp to Cortex Distance of Left Primary Motor Cortex and Its Computational Head Model: Implications for Personalized Neuromodulation.
    CNS Neuroscience & Therapeutics 2019; 25(11): 1270-1276.
OTHER INFORMATION:
  • Committee Member, Brain mapping group, China Image Graphics Society (CSIG), since 11/2021
  • Committee Member, Brain Connects, since 07/2019
  • Member, IEEE Brain, since 05/2020
  • Member, International Neuromodulation Society, since 10/2018
  • Member, International Parkinson and Movement Disorder Society, since 08/2018
  • Member, The Chinese Neuroscience Society, since 09/2017
  • Member, Asian Society Against Dementia, since 09/2016
  • Member, International Psychogeriatric Association, since 09/2015
  • Member, Organization for Human Brain Mapping, since 05/2012
 
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Department of Psychiatry, Faculty of Medicine.
The Chinese University of Hong Kong

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