Prof. Y.K. WING
Professor (Clinical) & Chairman
Choh-Ming Li Professor of Psychiatry

• Director of Li Chiu Kong Family Sleep Assessment Unit

• Awarded by Chinese Sleep Research Society for distinguished contributions to the development of sleep medicine and sleep research in May 2016
• Awarded the distinguished national award for Sleep Medicine Scientific Technological Advance in China by the Chinese Medical Doctor Association in September 2010, Beijing, China

• Sleep medicine
• Biological and cultural psychiatry
• Neuropsychiatry
• Transcultural psychopharmacology
• Digital mental health

(In a capacity of PI/Co-PI)

• Title: Family-based association study in idiopathic rapid eye movement sleep behavior disorder: a two-phase study using whole exome sequencing (From 2023 to 2025)
Funding source: Collaborative Research Fund (RGC GRF)
Position: PI

• Title: Digital mental health in depression – deep phenotyping and monitoring (From 2022 to 2024)
Funding source: Health and Medical Research Fund (HMRF)
Position: PI

• Title: Progression of prodromal markers of α-synucleinopathy neurodegeneration in the first-degree relatives of patients with REM sleep behavior disorder: a 7-year prospective study (From 2021 to 2025)
Funding source: General Research Fund (RGC GRF)
Position: PI

• Title: Multi-modal approaches to determine digital clinical phenotyping, novel proteomic biomarkers, and microbiota-host responses of REM sleep behavior disorder, a prodromal stage of α-synucleinopathy neurodegeneration, in a prospective family cohort (From 2022 to 2025)
Funding source: Collaborative Research Fund (RGC CRF)
Position: PI

• Title: Striatal dopamine transmission and prodromal markers of α-synucleinopathy neurodegeneration in recurrent dream enactment behaviors without REM sleep without atonia: a case-control study (From 2021 to 2024)
Funding source: General Research Fund (RGC GRF)
Position: PI

• Title: Gut microbiota in major depressive disorders with and without Rapid Eye Movement Behaviour Disorder: tracing a subtype of depression with underlying neurodegeneration (From 2021 to 2024)
Funding source: Health and Medical Research Fund (HMRF)
Position: PI

• Title: A 7-year prospective study of idiopathic REM sleep behavior disorder cohort in Chinese population: determining the optimal characteristics of prodromal markers to predict neurodegenerative diseases (From 2019 to 2023)
Funding source: Health and Medical Research Fund (HMRF)
Position: PI

• Title: Neuropsychiatric ‘long-COVID’ in adult patients (From 2022 to 2023)
Funding source: Collaborative Research Fund (RGC CRF)
Position: Co-PI

• Title: Psychological resilience and mental wellness: Effects of internal neurobiological affective and external social support system (From 2020 to 2023)
Funding: Collaborative Research Fund (CRF)
Position: Co-PI

(In a capacity of Co-I)

• Title: Effects of cognitive behavioral therapy and bright light therapy in youth with unipolar depression and evening chronotype: An assessor-blind, parallel-group, randomized controlled trial (From 2023 to 2025)
Funding source: General Research Fund (GRF)
Position: Co-I

• Title: An Artificial Intelligence chatbot for sleep education (From 2022 to 2024)
Funding source: Knowledge Transfer Project Fund
Position: Co-I

• Title: Randomized placebo – and active -controlled trial for assessing the efficacy of bright light therapy for sleep and mood symptoms in patients with Parkinson’s disease (From 2022 to 2025)
Funding source: Health and Medical Research Fund (HMRF)
Position: Co-I

• Title: Prevention of insomnia in at risk youth: A randomized controlled trial comparing cognitive behavioral prevention program for insomnia with active control condition (From 2022 to 2024)
Funding source: General Research Fund (GRF)
Position: Co-I

1. Huang B, Chau SWH, Liu Y, Chan JWY, Wang J, Ma SL, Zhang J, Chan PKS, Yeoh YK, Chen Z, Zhou L, Wong SH, Mok VCT, To KF, Lai HM, Ng S, Trenkwalder C, Chan FKL, Wing YK.
   Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives.
   Nature Communications. 2023 May 2;14(1):2501.
2. Morin CM, Bei B, Bjorvatn B, Poyares D, Spiegelhalder K, Wing YK.
   Governing Council of the World Sleep Society. World sleep society international sleep medicine guidelines position statement endorsement of “behavioral and psychological treatments for chronic insomnia disorder in adults: An American Academy of sleep medicine clinical practice guidelines”.
   Sleep Medicine. 2023 Jul 4;109:164-169.
3. Wang J, Lam SP, Huang B, Liu Y, Zhang J, Yu MWM, Tsang JCC, Zhou L, Chau SWH, Chan NY, Chan JWY, Schenck CH, Li SX, Mok VCT, Ma KKY, Chan AYY, Wing YK.
   Familial α-synucleinopathy spectrum features in patients with psychiatric REM sleep behaviour disorder.
   Journal of Neurology, Neurosurgery, and Psychiatry. 2023 Jun 30: jnnp-2022-330922.
4. Chan NY, Wu WJ, Chan JWY, Chan KCC, Li AM, Chan SSM, Hau KT, Wing YK.
   Sleep and academic performance among students in Hong Kong: Curvilinear relationship suggesting an optimal amount of sleep.
   Sleep Medicine. 2023 Jun; 106:97-105.
5. Feng H, Yang L, Liang YY, Ai S, Liu Y, Liu Y, Jin X, Lei B, Wang J, Zheng N, Chen X, Chan JWY, Sum RKW, Chan NY, Tan X, Benedict C, Wing YK, Zhang J.
   Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study.
   Nature Communications. 2023 Feb 18;14(1):930.
6. Liu Y, Partinen E, Chan NY, Dauvilliers Y, Inoue Y, De Gennaro L, Plazzi G, Bolstad CJ, Nadorff MR, Merikanto I, Bjorvatn B, Han F, Zhang B, Cunha AS, Mota-Rolim S, Léger D, Matsui K, Espie CA, Chung F, Morin CM, Sieminski M, Penzel T, Holzinger B, Partinen M, Wing YK.
   Dream-enactment behaviours during the COVID-19 pandemic: an international COVID-19 sleep study.
   Journal of Sleep Research. 2023 Feb;32(1):e13613.
7. Chen J, Li CT, Li TMH, Chan NY, Chan JWY, Liu Y, Lee TMC, Wing YK.
   A forgotten sign of depression – the omega sign and its implication.
   Asian Journal of Psychiatry. 2023 Feb;80:103345.
8. Lai HM, Tang Y, Lau ZYH, Campbell RAA, Yau JCN, Chan CCY, Chan DCW, Wong TY, Wong HKT, Yan LYC, Wu WKK, Wong SH, Kwok KW, Wing YK, Lam HHN, Ng HK, Mrsic-Flogel TD, Mok VCT, Chan JYK, Ko H.
   Antibody stabilization for thermally accelerated deep immunostaining.
   Nature Methods. 2022 Sep;19(9):1137-1146.
9. Chen CX, Li TMH, Zhang J, Li SX, Yu MWM, Tsang CC, Chan KCC, Au CT, Li AM, Kong APS, Chan JWY, Wing YK, Chan NY.
   The impact of sleep-corrected social jetlag on mental health, behavioral problems, and daytime sleepiness in adolescents.
   Sleep Medicine. 2022 Dec;100:494-500.
10. Chan JW, Lam SP, Li SX, Chau SW, Chan SY, Chan NY, Zhang JH, Wing YK.
    Adjunctive bright light treatment with gradual advance in unipolar major depressive disorder with evening chronotype – A randomized controlled trial.
    Psychological Medicine. 2022 Jun;52(8):1448-1457.